癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FMNL2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant FMNL2.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q96PY5 |
| Other Accession | BC036492 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 2B4 |
| Calculated MW | 123321 Da |
| Gene ID | 114793 |
|---|---|
| Other Names | Formin-like protein 2, Formin homology 2 domain-containing protein 2, FMNL2, FHOD2, KIAA1902 |
| Target/Specificity | FMNL2 (AAH36492, 1 a.a. ~ 178 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FMNL2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq]
REFERENCES
1.Down-regulation of formin-like 2 predicts poor prognosis in hepatocellular carcinoma.Liang L, Guan J, Zeng Y, Wang J, Li X, Zhang X, Ding Y.Hum Pathol. 2011 Apr 13. [Epub ahead of print]2.FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma.Zhu XL, Zeng YF, Guan J, Li YF, Deng YJ, Bian XW, Ding YQ, Liang L.J Pathol. 2011 Jul;224(3):377-88. doi: 10.1002/path.2871. Epub 2011 Apr 19.3.FMNL2 enhances invasion of colorectal carcinoma by inducing epithelial mesenchymal transition.Li Y, Zhu X, Zeng Y, Wang J, Zhang X, Ding YQ, Liang L.Mol Cancer Res. 2010 Dec;8(12):1579-90. Epub 2010 Nov 11.4.Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC.Kitzing TM, Wang Y, Pertz O, Copeland JW, Grosse R.Oncogene. 2010 Jan 25. [Epub ahead of print]5.Overexpression of FMNL2 is closely related to metastasis of colorectal cancer.Zhu XL, Liang L, Ding YQ.Int J Colorectal Dis. 2008 Nov;23(11):1041-7. Epub 2008 Jul 30.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
