癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GNA13 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant GNA13.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q14344 |
| Other Accession | BC036756 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 6F6-B5 |
| Calculated MW | 44050 Da |
| Gene ID | 10672 |
|---|---|
| Other Names | Guanine nucleotide-binding protein subunit alpha-13, G alpha-13, G-protein subunit alpha-13, GNA13 |
| Target/Specificity | GNA13 (AAH36756, 1 a.a. ~ 377 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GNA13 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Critical role of G(alpha)12 and G(alpha)13 for human small cell lung cancer cell proliferation in vitro and tumor growth in vivo. Grzelinski M, et al. Clin Cancer Res, 2010 Mar 1. PMID 20160064.G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin outside-in signaling. Gong H, et al. Science, 2010 Jan 15. PMID 20075254.Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells. Saito M, et al. Cell Signal, 2010 Jan. PMID 19772916.Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency. Chen L, et al. J Biol Chem, 2009 Oct 2. PMID 19654325.
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