癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GSC Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant GSC.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P56915 |
| Other Accession | NM_173849 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3D11 |
| Calculated MW | 28150 Da |
| Gene ID | 145258 |
|---|---|
| Other Names | Homeobox protein goosecoid, GSC |
| Target/Specificity | GSC (NP_776248, 151 a.a. ~ 257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GSC Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
REFERENCES
Pedigree and genetic study of a bilateral congenital microtia family. Zhang Q, et al. Plast Reconstr Surg, 2010 Mar. PMID 20195123.Environmental and genetic factors associated with congenital microtia: a case-control study in Jiangsu, China, 2004 to 2007. Zhang QG, et al. Plast Reconstr Surg, 2009 Oct. PMID 19935299.A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Paterson AD, et al. Diabetes, 2010 Feb. PMID 19875614.A child with deletion (14)(q24.3q32.13) and auditory neuropathy. Schlade-Bartusiak K, et al. Am J Med Genet A, 2008 Jan 1. PMID 18074379.The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Hartwell KA, et al. Proc Natl Acad Sci U S A, 2006 Dec 12. PMID 17142318.
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