癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HAPLN4 Antibody (monoclonal) (M12)
Mouse monoclonal antibody raised against a partial recombinant HAPLN4.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q86UW8 |
| Other Accession | NM_023002 |
| Reactivity | Human, Mouse |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG3 Kappa |
| Clone Names | 1G5 |
| Calculated MW | 42801 Da |
| Gene ID | 404037 |
|---|---|
| Other Names | Hyaluronan and proteoglycan link protein 4, Brain link protein 2, HAPLN4, BRAL2, KIAA1926 |
| Target/Specificity | HAPLN4 (NP_075378, 30 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HAPLN4 Antibody (monoclonal) (M12) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas. Sim H, et al. J Biol Chem, 2009 Sep 25. PMID 19633295.Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets. Bekku Y, et al. Mol Cell Neurosci, 2003 Sep. PMID 14550776.A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links. Spicer AP, et al. J Biol Chem, 2003 Jun 6. PMID 12663660.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. Nagase T, et al. DNA Res, 2001 Aug 31. PMID 11572484.
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