癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HIP1R Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HIP1R.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | O75146 |
| Other Accession | NM_003959 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3E11 |
| Calculated MW | 119388 Da |
| Gene ID | 9026 |
|---|---|
| Other Names | Huntingtin-interacting protein 1-related protein, HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R, HIP12, KIAA0655 |
| Target/Specificity | HIP1R (NP_003950, 969 a.a. ~ 1066 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HIP1R Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.HIP1R interacts with a member of Bcl-2 family, BCL2L10, and induces BAK-dependent cell death. Kim JH, et al. Cell Physiol Biochem, 2009. PMID 19255499.Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain. Wilbur JD, et al. J Biol Chem, 2008 Nov 21. PMID 18790740.Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Poupon V, et al. Proc Natl Acad Sci U S A, 2008 Jan 8. PMID 18165318.Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. Parker JA, et al. J Neurosci, 2007 Oct 10. PMID 17928447.
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