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HOXA7 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant HOXA7.

     
  • 1 - HOXA7 Antibody (monoclonal) (M01) AT2407a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.79 KDa) .
  • 1 - HOXA7 Antibody (monoclonal) (M01) AT2407a
    Western Blot analysis of HOXA7 expression in transfected 293T cell line by HOXA7 monoclonal antibody (M01), clone 2F2.

    Lane 1: HOXA7 transfected lysate(25.4 KDa).
    Lane 2: Non-transfected lysate.
  • 10 - HOXA7 Antibody (monoclonal) (M01) AT2407a
    Detection limit for recombinant GST tagged HOXA7 is approximately 0.1ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P31268
Other Accession NM_006896
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2a Kappa
Clone Names 2F2
Calculated MW 25355 Da
Additional Information
Gene ID 3204
Other Names Homeobox protein Hox-A7, Homeobox protein Hox 11, Homeobox protein Hox-1A, HOXA7, HOX1A
Target/Specificity HOXA7 (NP_008827, 58 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsHOXA7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.

REFERENCES

1.HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.Chung N, Jee BK, Chae SW, Jeon YW, Lee KH, Rha HK.Mol Biol Rep. 2009 Feb;36(2):227-35. Epub 2007 Oct 30.

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