癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HRASLS3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HRASLS3.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P53816 |
| Other Accession | BC001387 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1B10-2D9 |
| Calculated MW | 17937 Da |
| Gene ID | 11145 |
|---|---|
| Other Names | HRAS-like suppressor 3, HRSL3, Adipose-specific phospholipase A2, AdPLA, Group XVI phospholipase A1/A2, H-rev 107 protein homolog, HRAS-like suppressor 1, HREV107-1, HREV107-3, Renal carcinoma antigen NY-REN-65, PLA2G16, HRASLS3, HREV107 |
| Target/Specificity | HRASLS3 (AAH01387, 1 a.a. ~ 162 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HRASLS3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. Uyama T, et al. Biochim Biophys Acta, 2009 Dec. PMID 19615464.AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Jaworski K, et al. Nat Med, 2009 Feb. PMID 19136964.Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). Duncan RE, et al. J Biol Chem, 2008 Sep 12. PMID 18614531.Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells. Nazarenko I, et al. J Cell Sci, 2007 Apr 15. PMID 17374643.H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling. Nazarenko I, et al. Am J Pathol, 2006 Oct. PMID 17003497.
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