癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IFT57 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant IFT57.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9NWB7 |
| Other Accession | NM_018010 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1G8 |
| Calculated MW | 49108 Da |
| Gene ID | 55081 |
|---|---|
| Other Names | Intraflagellar transport protein 57 homolog, Dermal papilla-derived protein 8, Estrogen-related receptor beta-like protein 1, HIP1-interacting protein, MHS4R2, IFT57, DERP8, ESRRBL1, HIPPI |
| Target/Specificity | IFT57 (NP_060480, 214 a.a. ~ 312 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | IFT57 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. Gdynia G, et al. Apoptosis, 2008 Mar. PMID 18188704.Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo. Majumder P, et al. Biochem Biophys Res Commun, 2007 Feb 2. PMID 17173859.Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1. Banerjee M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006 Dec 1. PMID 17142908.Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1. Majumder P, et al. Neurobiol Dis, 2006 May. PMID 16364650.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
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