癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ITGB7 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ITGB7.
- 产品详情
- 实验流程
Application 
| IF |
|---|---|
| Primary Accession | P26010 |
| Other Accession | NM_000889 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 8D3 |
| Calculated MW | 86903 Da |
| Gene ID | 3695 |
|---|---|
| Other Names | Integrin beta-7, Gut homing receptor beta subunit, ITGB7 |
| Target/Specificity | ITGB7 (NP_000880, 401 a.a. ~ 505 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ITGB7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1. Cicala C, et al. Proc Natl Acad Sci U S A, 2009 Dec 8. PMID 19933330.The regulation mechanism for the auto-inhibition of binding of human filamin A to integrin. Pentik?inen U, et al. J Mol Biol, 2009 Oct 30. PMID 19699211.Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. Lad Y, et al. J Biol Chem, 2008 Dec 12. PMID 18829455.AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons. Monteiro P, et al. Biochem Biophys Res Commun, 2007 Jun 29. PMID 17490615.Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis. Le Floc'h A, et al. J Exp Med, 2007 Mar 19. PMID 17325197.
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