癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LGR7 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant LGR7.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HBX9 |
| Other Accession | NM_021634 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3E4 |
| Calculated MW | 86975 Da |
| Gene ID | 59350 |
|---|---|
| Other Names | Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1, RXFP1, LGR7 |
| Target/Specificity | LGR7 (NP_067647, 68 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | LGR7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment.Jelinic M, Leo CH, Uiterweer ED, Sandow SL, Gooi JH, Wlodek ME, Conrad KP, Parkington H, Tare M, Parry LJFASEB J. 2014 Jan;28(1):275-87. doi: 10.1096/fj.13-233429. Epub 2013 Sep 13.2.Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice.Soh YM, Tiwari A, Mahendroo M, Conrad KP, Parry LJ.Endocrinology. 2012 Dec;153(12):6054-64. doi: 10.1210/en.2012-1577. Epub 2012 Oct 19.3.Effect of Relaxin on Human Sperm Functions and Fertilizing Ability.Ferlin A, Menegazzo M, Gianesello L, Selice R, Foresta C.J Androl. 2011 Sep 8.4.Primate preimplantation embryo is a target for relaxin during early pregnancy.Vandevoort CA, Mtango NR, Latham KE, Stewart DR.Fertil Steril. 2011 Jul;96(1):203-7. Epub 2011 Jun 8.5.Suppression of Relaxin Receptor RXFP1 Decreases Prostate Cancer Growth and Metastasis.Feng S, Agoulnik I, Truong A, Li Z, Creighton CJ, Kaftanovskaya EM, Pereira R, Han HD, Lopez-Berestein G, Klonisch T, Ittmann M, Sood A, Agoulnik A.Endocr Relat Cancer. 2010 Sep 24. [Epub ahead of print]6.Decreased Expression of the Rat Myometrial Relaxin Receptor (RXFP1) in Late Pregnancy Is Partially Mediated by the Presence of the Conceptus.Vodstrcil LA, Shynlova O, Verlander JW, Wlodek ME, Parry LJ.Biol Reprod. 2010 Aug 4. [Epub ahead of print]7.Relaxin stimulates osteoclast differentiation and activation.Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C.Bone. 2009 Oct 12. [Epub ahead of print]8.Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1 transfected HEK293 cells.Kern A, Bryant-Greenwood GD.Endocrinology. 2009 May;150(5):2419-28. Epub 2008 Dec 30.
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