癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LMO4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant LMO4.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P61968 |
| Other Accession | BC017673 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Lambda |
| Clone Names | 4H8 |
| Calculated MW | 17994 Da |
| Gene ID | 8543 |
|---|---|
| Other Names | LIM domain transcription factor LMO4, Breast tumor autoantigen, LIM domain only protein 4, LMO-4, LMO4 |
| Target/Specificity | LMO4 (AAH17673, 1 a.a. ~ 165 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | LMO4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene.
REFERENCES
Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder. Ribas?s M, et al. Biol Psychiatry, 2009 Nov 15. PMID 19733838.LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression. Monta?ez-Wiscovich ME, et al. Oncogene, 2009 Oct 15. PMID 19648968.Genome-wide and candidate gene association study of cigarette smoking behaviors. Caporaso N, et al. PLoS One, 2009. PMID 19247474.Transcription factor Lmo4 defines the shape of functional areas in developing cortices and regulates sensorimotor control. Huang Z, et al. Dev Biol, 2009 Mar 1. PMID 19111533.LIM only 4 is overexpressed in late stage pancreas cancer. Yu J, et al. Mol Cancer, 2008 Dec 22. PMID 19099607.
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