癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
LY75 Antibody (monoclonal) (M10)
Mouse monoclonal antibody raised against a partial recombinant LY75.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | O60449 |
| Other Accession | NM_002349 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3G4 |
| Calculated MW | 198311 Da |
| Gene ID | 100526664;4065 |
|---|---|
| Other Names | Lymphocyte antigen 75, Ly-75, C-type lectin domain family 13 member B, DEC-205, gp200-MR6, CD205, LY75, CD205, CLEC13B |
| Target/Specificity | LY75 (NP_002340, 37 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | LY75 Antibody (monoclonal) (M10) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity. Stumpf AN, et al. Blood, 2009 Oct 22. PMID 19706888.oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation. Nickel T, et al. Atherosclerosis, 2009 Aug. PMID 19203752.Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Gurer C, et al. Blood, 2008 Aug 15. PMID 18519810.Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. Nonaka D, et al. Am J Surg Pathol, 2007 Jul. PMID 17592270.
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