癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MEOX1 Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant MEOX1.
- 产品详情
- 实验流程
- 背景知识
Application 
| IF, E |
|---|---|
| Primary Accession | P50221 |
| Other Accession | NM_004527 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4B11 |
| Calculated MW | 27997 Da |
| Gene ID | 4222 |
|---|---|
| Other Names | Homeobox protein MOX-1, Mesenchyme homeobox 1, MEOX1, MOX1 |
| Target/Specificity | MEOX1 (NP_004518.1, 165 a.a. ~ 252 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MEOX1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.
REFERENCES
Diaphanospondylodysostosis: six new cases and exclusion of the candidate genes, PAX1 and MEOX1. Vatanavicharn N, et al. Am J Med Genet A, 2007 Oct 1. PMID 17764081.The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Wissm?ller S, et al. Nucleic Acids Res, 2006. PMID 16582099.Hedgehog signaling induces cardiomyogenesis in P19 cells. Gianakopoulos PJ, et al. J Biol Chem, 2005 Jun 3. PMID 15793308.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Disruption of Meox or Gli activity ablates skeletal myogenesis in P19 cells. Petropoulos H, et al. J Biol Chem, 2004 Jun 4. PMID 15039437.
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