癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MFRP Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant MFRP.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q9BXJ0 |
| Other Accession | NM_031433 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Lambda |
| Clone Names | 1.0E+12 |
| Calculated MW | 25298 Da |
| Gene ID | 114902 |
|---|---|
| Other Names | Complement C1q tumor necrosis factor-related protein 5, C1QTNF5, CTRP5 |
| Target/Specificity | MFRP (NP_113621, 480 a.a. ~ 579 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MFRP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.
REFERENCES
A detailed phenotypic assessment of individuals affected by MFRP-related oculopathy. Mukhopadhyay R, et al. Mol Vis, 2010 Mar 26. PMID 20361016.Compound heterozygosity for a novel and a recurrent MFRP gene mutation in a family with the nanophthalmos-retinitis pigmentosa complex. Zenteno JC, et al. Mol Vis, 2009 Sep 5. PMID 19753314.Evaluation of MFRP as a candidate gene for high hyperopia. Wang P, et al. Mol Vis, 2009. PMID 19169412.The association of membrane frizzled-related protein (MFRP) gene with acute angle-closure glaucoma--a pilot study. Wang IJ, et al. Mol Vis, 2008 Sep 8. PMID 18781223.Molecular analysis of CHX10 and MFRP in Chinese subjects with primary angle closure glaucoma and short axial length eyes. Aung T, et al. Mol Vis, 2008 Jul 17. PMID 18648522.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
