MTF1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant MTF1.
- 产品详情
- 实验流程
- 背景知识
| Application  
 | WB, E | 
|---|---|
| Primary Accession | Q14872 | 
| Other Accession | NM_005955 | 
| Reactivity | Human | 
| Host | mouse | 
| Clonality | monoclonal | 
| Isotype | IgG2a Kappa | 
| Clone Names | 2E6 | 
| Calculated MW | 80957 Da | 
| Gene ID | 4520 | 
|---|---|
| Other Names | Metal regulatory transcription factor 1, MRE-binding transcription factor, Transcription factor MTF-1, MTF1 | 
| Target/Specificity | MTF1 (NP_005946, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | 
| Dilution | WB~~1:500~1000 E~~N/A | 
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . | 
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | 
| Precautions | MTF1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | 
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).
REFERENCES
1.Fetal Exposure to Cocaine Causes Programming of Prkce Gene Repression in the Left Ventricle of Adult Rat Offspring.Zhang H, Meyer KD, Zhang L.Biol Reprod. 2009 Mar;80(3):440-8. Epub 2008 Oct 22

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