癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MYT1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant MYT1.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q01538 |
| Other Accession | NM_004535 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Lambda |
| Clone Names | 2A7 |
| Calculated MW | 122329 Da |
| Gene ID | 4661 |
|---|---|
| Other Names | Myelin transcription factor 1, MyT1, Myelin transcription factor I, MyTI, PLPB1, Proteolipid protein-binding protein, MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1 |
| Target/Specificity | MYT1 (NP_004526, 586 a.a. ~ 685 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | MYT1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
REFERENCES
c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer. Choi HS, et al. Mol Cell Biol, 2009 Apr. PMID 19204086.Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. Vega A, et al. Gynecol Oncol, 2009 Jan. PMID 18950845.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS. Vana AC, et al. Glia, 2007 May. PMID 17330875.Myelin transcription factor 1 (Myt1) modulates the proliferation and differentiation of oligodendrocyte lineage cells. Nielsen JA, et al. Mol Cell Neurosci, 2004 Jan. PMID 14962745.
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