癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NKIRAS1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant NKIRAS1.
- 产品详情
- 实验流程
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q9NYS0 |
| Other Accession | BC012145 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2A7 |
| Calculated MW | 21643 Da |
| Gene ID | 28512 |
|---|---|
| Other Names | NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1, NKIRAS1, KBRAS1 |
| Target/Specificity | NKIRAS1 (AAH12145, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NKIRAS1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas. Gerashchenko GV, et al. Exp Oncol, 2010 Jul. PMID 20693965.Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis. Dieguez-Gonzalez R, et al. Ann Rheum Dis, 2009 Apr. PMID 18434448.High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles M, et al. Science, 2005 Mar 11. PMID 15761153.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras. Chen Y, et al. Mol Cell Biol, 2004 Apr. PMID 15024091.
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