癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NR2E1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant NR2E1.
- 产品详情
- 实验流程
Application 
| IF |
|---|---|
| Primary Accession | Q9Y466 |
| Other Accession | NM_003269 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4D2 |
| Calculated MW | 42589 Da |
| Gene ID | 7101 |
|---|---|
| Other Names | Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1, TLX |
| Target/Specificity | NR2E1 (NP_003260, 249 a.a. ~ 342 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NR2E1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Liu HK, et al. Genes Dev, 2010 Apr 1. PMID 20360385.Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX. Iwahara N, et al. Biochem Biophys Res Commun, 2009 Sep 4. PMID 19555662.A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, et al. Biol Psychiatry, 2009 Apr 1. PMID 19058789.Transrepressive function of TLX requires the histone demethylase LSD1. Yokoyama A, et al. Mol Cell Biol, 2008 Jun. PMID 18391013.Initial association of NR2E1 with bipolar disorder and identification of candidate mutations in bipolar disorder, schizophrenia, and aggression through resequencing. Kumar RA, et al. Am J Med Genet B Neuropsychiatr Genet, 2008 Sep 5. PMID 18205168.
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