癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NUCB1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant NUCB1.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q02818 |
| Other Accession | BC002356 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1H8-2C11 |
| Calculated MW | 53879 Da |
| Gene ID | 4924 |
|---|---|
| Other Names | Nucleobindin-1, CALNUC, NUCB1, NUC |
| Target/Specificity | NUCB1 (AAH02356, 28 a.a. ~ 461 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NUCB1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events.
REFERENCES
Calnuc: Emerging roles in calcium signaling and human diseases. Aradhyam GK, et al. IUBMB Life, 2010 Jun. PMID 20503436.A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site. Tsukumo Y, et al. J Biol Chem, 2009 Oct 2. PMID 19656946.Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products. Nagase T, et al. DNA Res, 2008 Jun 30. PMID 18316326.Modulation of nucleobindin-1 and nucleobindin-2 by caspases. Valencia CA, et al. FEBS Lett, 2008 Jan 23. PMID 18154733.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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