癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PAI-RBP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant PAI-RBP1.
- 产品详情
- 实验流程
Application 
| WB, IF |
|---|---|
| Primary Accession | Q8NC51 |
| Other Accession | BC002488 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1D2-2E9 |
| Calculated MW | 44965 Da |
| Gene ID | 26135 |
|---|---|
| Other Names | Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, SERPINE1 mRNA-binding protein 1, SERBP1, PAIRBP1 |
| Target/Specificity | PAI-RBP1 (AAH02488, 1 a.a. ~ 402 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PAI-RBP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.Localization of SERBP1 in stress granules and nucleoli.Lee YJ, Wei HM, Chen LY, Li CFEBS J. 2013 Nov 8. doi: 10.1111/febs.12606.2.Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution.Lee YJ, Hsieh WY, Chen LY, Li C.J Cell Biochem. 2012 Mar 22. doi: 10.1002/jcb.24151. [Epub ahead of print]3.Serologic Markers of Effective Tumor Immunity against Chronic Lymphocytic Leukemia Include Nonmutated B-Cell Antigens.Marina O, Hainz U, Biernacki MA, Zhang W, Cai A, Duke-Cohan JS, Liu F, Brusic V, Neuberg D, Kutok JL, Alyea EP, Canning CM, Soiffer RJ, Ritz J, Wu CJ.Cancer Res. 2010 Feb 15;70(4):1344-55. Epub 2010 Feb 2.4.An integrated approach of differential mass spectrometry and gene ontology analysis identified novel proteins regulating neuronal differentiation and survival.Kobayashi D, Kumagai J, Morikawa T, Wilson-Morifuji M, Wilson A, Irie A, Araki N.Mol Cell Proteomics. 2009 Oct;8(10):2350-67. Epub 2009 Jun 13.5.Rapid Changes of mRNA-binding Protein Levels following Glucose and 3-Isobutyl-1-methylxanthine Stimulation of Insulinoma INS-1 CellsSus C, Czupalla C, Winter C, Pursche T, Knoch KP, Schroeder M, Hoflack B, Solimena M.Mol Cell Proteomics. 2009 Mar;8(3):393-408. Epub 2008 Oct 14.
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