癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PBX1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PBX1.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | P40424 |
| Other Accession | NM_002585 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4A2 |
| Calculated MW | 46626 Da |
| Gene ID | 5087 |
|---|---|
| Other Names | Pre-B-cell leukemia transcription factor 1, Homeobox protein PBX1, Homeobox protein PRL, PBX1, PRL |
| Target/Specificity | PBX1 (NP_002576, 213 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PBX1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.PBX1 Genomic Pioneer Function Drives ER alpha Signaling Underlying Progression in Breast Cancer.Magnani L, Ballantyne EB, Zhang X, Lupien M.PLoS Genet. 2011 Nov;7(11):e1002368. Epub 2011 Nov 17.2.Cooperative transcriptional activation by klf4, meis2, and pbx1.Bjerke GA, Hyman-Walsh C, Wotton D.Mol Cell Biol. 2011 Sep;31(18):3723-33. Epub 2011 Jul 11.3.Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW.Hum Mol Genet. 2009 Feb 15;18(4):679-87. Epub 2008 Dec 8.
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