癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PBX4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant PBX4.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BYU1 |
| Other Accession | NM_025245 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1D8 |
| Calculated MW | 40854 Da |
| Gene ID | 80714 |
|---|---|
| Other Names | Pre-B-cell leukemia transcription factor 4, Homeobox protein PBX4, PBX4 |
| Target/Specificity | PBX4 (NP_079521, 319 a.a. ~ 374 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PBX4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a homeodomain protein with similarity to a transcription factor involved in translocations in pre-B-cell leukemias. The presence of a homeobox domain suggests that this protein acts as a transcription factor, but this function has not been demonstrated.
REFERENCES
Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Hu M, et al. Pharmacogenet Genomics, 2010 Oct. PMID 20679960.Common variants at 30 loci contribute to polygenic dyslipidemia. Kathiresan S, et al. Nat Genet, 2009 Jan. PMID 19060906.Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. Tai ES, et al. J Lipid Res, 2009 Mar. PMID 18987386.Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Kathiresan S, et al. Nat Genet, 2008 Feb. PMID 18193044.Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Willer CJ, et al. Nat Genet, 2008 Feb. PMID 18193043.
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