癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PLXNC1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant PLXNC1.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | O60486 |
| Other Accession | NM_005761 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 1A12 |
| Calculated MW | 175742 Da |
| Gene ID | 10154 |
|---|---|
| Other Names | Plexin-C1, Virus-encoded semaphorin protein receptor, CD232, PLXNC1, VESPR |
| Target/Specificity | PLXNC1 (NP_005752, 250 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | PLXNC1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. Lazova R, et al. Am J Dermatopathol, 2009 Apr. PMID 19318806.Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression. Scott GA, et al. J Invest Dermatol, 2009 Apr. PMID 18987670.Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease. Li Y, et al. PLoS One, 2008 Jul 16. PMID 18628988.Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins. Scott GA, et al. J Invest Dermatol, 2008 Jan. PMID 17671519.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.
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