癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RAB4A Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant RAB4A.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P20338 |
| Other Accession | BC004309 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1C10 |
| Calculated MW | 24390 Da |
| Gene ID | 5867 |
|---|---|
| Other Names | Ras-related protein Rab-4A, RAB4A, RAB4 |
| Target/Specificity | RAB4A (AAH04309, 1 a.a. ~ 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RAB4A Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. Eggers CT, et al. J Biol Chem, 2009 Nov 20. PMID 19797056.Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway. Yudowski GA, et al. Mol Biol Cell, 2009 Jun. PMID 19369423.VEGFR1 (Flt1) regulates Rab4 recycling to control fibronectin polymerization and endothelial vessel branching. Jones MC, et al. Traffic, 2009 Jun. PMID 19302266.Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. Fernandez DR, et al. J Immunol, 2009 Feb 15. PMID 19201859.Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 short cycle. Conti F, et al. Am J Physiol Endocrinol Metab, 2009 Mar. PMID 19126785.
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