癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RALBP1 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant RALBP1.
- 产品详情
- 实验流程
Application 
| WB, IP, E |
|---|---|
| Primary Accession | Q15311 |
| Other Accession | BC013126 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2A1 |
| Calculated MW | 76063 Da |
| Gene ID | 10928 |
|---|---|
| Other Names | RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76 |
| Target/Specificity | RALBP1 (AAH13126.1, 1 a.a. ~ 655 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RALBP1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.Dual effects of Ral-activated pathways on p27 localization and TGF-?] signaling.Tazat K, Harsat M, Goldshmid-Shagal A, Ehrlich M, Henis YIMol Biol Cell. 2013 Jun;24(11):1812-24. doi: 10.1091/mbc.E13-01-0007. Epub 2013 Apr 10.2.The RalB Small GTPase Mediates Invadopodia Formation Through a GTPase Activating Protein-independent Function of the RalBP1/RLIP76 Effector.Neel NF, Rossman KL, Martin TD, Hayes TK, Yeh JJ, Der CJ.Mol Cell Biol. 2012 Feb 13. [Epub ahead of print]3.Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: the role of targeting signals and of protein-protein interactions.Fillatre J, Delacour D, Van Hove L, Bagarre T, Houssin N, Soulika M, Veitia RA, Moreau J.FASEB J. 2012 Feb 8. [Epub ahead of print]4.Ras-Related Small GTPases RalA and RalB Regulate Cellular Survival After Ionizing Radiation.Kidd AR 3rd, Snider JL, Martin TD, Graboski SF, Der CJ, Cox AD.Int J Radiat Oncol Biol Phys. 2010 Jul 7. [Epub ahead of print]5.Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).Herlevsen MC, Theodorescu D.Biochem Biophys Res Commun. 2007 Oct 12;362(1):56-62. Epub 2007 Aug 8.6.Expression of Ral GTPases, Their Effectors, and Activators in Human Bladder Cancer.Smith SC, Oxford G, Baras AS, Owens C, Havaleshko D, Brautigan DL, Safo MK, Theodorescu D.Clin Cancer Res. 2007 Jul 1;13(13):3803-13.
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