癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RALGDS Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RALGDS.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | Q12967 |
| Other Accession | BC059362 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 1A11 |
| Calculated MW | 100607 Da |
| Gene ID | 5900 |
|---|---|
| Other Names | Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF, RALGDS, KIAA1308, RGF |
| Target/Specificity | RALGDS (AAH59362, 793 a.a. ~ 902 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RALGDS Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Ras classical effectors: new tales from in silico complexes. Fuentes G, et al. Trends Biochem Sci, 2009 Nov. PMID 19801192.RalA functions as an indispensable signal mediator for the nutrient-sensing system. Maehama T, et al. J Biol Chem, 2008 Dec 12. PMID 18948269.Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells. Rondaij MG, et al. Blood, 2008 Jul 1. PMID 18417737.No evidence of RALGDS mutations in cutaneous melanoma. Omholt K, et al. Melanoma Res, 2007 Dec. PMID 17992125.Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Yin J, et al. Mol Cell Biol, 2007 Nov. PMID 17709381.
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