癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RDX Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a full length recombinant RDX.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF |
|---|---|
| Primary Accession | P35241 |
| Other Accession | BC047109 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 1D9 |
| Calculated MW | 68564 Da |
| Gene ID | 5962 |
|---|---|
| Other Names | Radixin, RDX |
| Target/Specificity | RDX (AAH47109, 1 a.a. ~ 583 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RDX Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
REFERENCES
1.Radixin expression in microglia after cortical stroke lesion.Persson A, Osman A, Bolouri H, Mallard C, Kuhn HGGlia. 2013 Feb 26. doi: 10.1002/glia.22473.2.Molecular architecture of the chick vestibular hair bundle.Shin JB, Krey JF, Hassan A, Metlagel Z, Tauscher AN, Pagana JM, Sherman NE, Jeffery ED, Spinelli KJ, Zhao H, Wilmarth PA, Choi D, David LL, Auer M, Barr-Gillespie PG.Nat Neurosci. 2013 Jan 20. doi: 10.1038/nn.3312.3.Large membrane domains in hair bundles specify spatially constricted radixin activation.Zhao H, Williams DE, Shin JB, Brugger B, Gillespie PG.J Neurosci. 2012 Mar 28;32(13):4600-9.
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