癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RGL2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant RGL2.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | O15211 |
| Other Accession | BC032681 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 |
| Clone Names | 4D10 |
| Calculated MW | 83549 Da |
| Gene ID | 5863 |
|---|---|
| Other Names | Ral guanine nucleotide dissociation stimulator-like 2, RalGDS-like 2, RalGDS-like factor, Ras-associated protein RAB2L, RGL2, RAB2L |
| Target/Specificity | RGL2 (AAH32681, 644 a.a. ~ 743 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RGL2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.Castro AF, Campos T, Babcock JT, Armijo ME, Martinez-Conde A, Pincheira R, Quilliam LA.J Cell Biochem. 2011 Nov 17. doi: 10.1002/ jcb.23458.2.Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.Vigil D, Martin TD, Williams F, Yeh JJ, Campbell SL, Der CJ.J Biol Chem. 2010 Nov 5;285(45):34729-40. Epub 2010 Aug 27.
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