癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RNF123 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RNF123.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q5XPI4 |
| Other Accession | NM_022064 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3F8 |
| Calculated MW | 148515 Da |
| Gene ID | 63891 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase RNF123, 632-, Kip1 ubiquitination-promoting complex protein 1, RING finger protein 123, RNF123, KPC1 |
| Target/Specificity | RNF123 (NP_071347, 1216 a.a. ~ 1314 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | RNF123 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.
REFERENCES
1.Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination.Baugh JM, Viktorova EG, Pilipenko EV.J Mol Biol. 2009 Feb 27;386(3):814-27. Epub 2009 Jan 8.
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