癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SCN2B Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SCN2B.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | O60939 |
| Other Accession | BC036793 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 2G11-C12 |
| Calculated MW | 24326 Da |
| Gene ID | 6327 |
|---|---|
| Other Names | Sodium channel subunit beta-2, SCN2B |
| Target/Specificity | SCN2B (AAH36793, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SCN2B Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Sudden infant death syndrome-associated mutations in the sodium channel beta subunits. Tan BH, et al. Heart Rhythm, 2010 Jun. PMID 20226894.Mutations in sodium channel beta1- and beta2-subunits associated with atrial fibrillation. Watanabe H, et al. Circ Arrhythm Electrophysiol, 2009 Jun. PMID 19808477.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration. Kim DY, et al. J Biol Chem, 2005 Jun 17. PMID 15833746.
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