癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SH3PX3 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant SH3PX3.
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8WV41 |
| Other Accession | NM_153271 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3A1 |
| Calculated MW | 65265 Da |
| Gene ID | 257364 |
|---|---|
| Other Names | Sorting nexin-33, SH3 and PX domain-containing protein 3, SNX33, SH3PX3, SH3PXD3C, SNX30 |
| Target/Specificity | SH3PX3 (NP_695003, 475 a.a. ~ 574 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SH3PX3 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Voss M, et al. BMC Immunol, 2009 Oct 6. PMID 19807924.Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins. Kleino I, et al. J Cell Biochem, 2009 Nov 1. PMID 19718658.Sorting nexin 33 induces mammalian cell micronucleated phenotype and actin polymerization by interacting with Wiskott-Aldrich syndrome protein. Zhang J, et al. J Biol Chem, 2009 Aug 7. PMID 19487689.The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP shedding. Heiseke A, et al. Traffic, 2008 Jul. PMID 18419754.A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein. Sch?bel S, et al. J Biol Chem, 2008 May 23. PMID 18353773.
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