癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SLC20A1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant SLC20A1.
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Application 
| WB |
|---|---|
| Primary Accession | Q8WUM9 |
| Other Accession | BC019944 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a kappa |
| Clone Names | 6A9-F2 |
| Calculated MW | 73700 Da |
| Gene ID | 6574 |
|---|---|
| Other Names | Sodium-dependent phosphate transporter 1, Gibbon ape leukemia virus receptor 1, GLVR-1, Leukemia virus receptor 1 homolog, Phosphate transporter 1, PiT-1, Solute carrier family 20 member 1, SLC20A1, GLVR1, PIT1 |
| Target/Specificity | SLC20A1 (AAH19944, 1 a.a. ~ 679 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SLC20A1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Retrovirus receptors allow infection of human and murine cells by various retroviruses. The receptors that have been identified at the molecular level include CD4 (MIM 186940) for human immunodeficiency virus, Rec1 for murine ecotropic virus, and GLVR1 for gibbon ape leukemia virus (see MIM 182090). These 3 proteins show no homology to one another at the DNA or protein level. GLVR1 is a sodium-dependent phosphate symporter.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Identification of a novel function of PiT1 critical for cell proliferation and independent of its phosphate transport activity. Beck L, et al. J Biol Chem, 2009 Nov 6. PMID 19726692.Pit-1 mutation and lipoedema in a family. Bano G, et al. Exp Clin Endocrinol Diabetes, 2010 Jun. PMID 19609847.Expression of Pit-1 in nonsomatotrope cell lines induces human growth hormone locus control region histone modification and hGH-N transcription. Hogan KA, et al. J Mol Biol, 2009 Jul 3. PMID 19427323.
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