癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SLC25A6 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant SLC25A6.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P12236 |
| Other Accession | NM_001636 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG3 Kappa |
| Clone Names | 2A9 |
| Calculated MW | 32866 Da |
| Gene ID | 293 |
|---|---|
| Other Names | ADP/ATP translocase 3, ADP, ATP carrier protein 3, ADP, ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6, ADP/ATP translocase 3, N-terminally processed, SLC25A6, ANT3 |
| Target/Specificity | SLC25A6 (NP_001627, 135 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | SLC25A6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
REFERENCES
Molecular interactions between mitochondrial membrane proteins and the C-terminal domain of PB1-F2: an in silico approach. Danishuddin M, et al. J Mol Model, 2010 Mar. PMID 19669810.Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells. Hu Z, et al. FEBS Lett, 2009 Jan 22. PMID 19111545.Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells. Yang Z, et al. Mol Biol Cell, 2007 Nov. PMID 17855512.Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. Tu LC, et al. Mol Cell Proteomics, 2007 Apr. PMID 17220478.IL-4-induced upregulation of adenine nucleotide translocase 3 and its role in Th cell survival from apoptosis. Jang JY, et al. Cell Immunol, 2006 May. PMID 16930576.
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