癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
STK38 Antibody (monoclonal) (M11)
Mouse monoclonal antibody raised against a partial recombinant STK38.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q15208 |
| Other Accession | BC012085 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 2F6 |
| Calculated MW | 54190 Da |
| Gene ID | 11329 |
|---|---|
| Other Names | Serine/threonine-protein kinase 38, NDR1 protein kinase, Nuclear Dbf2-related kinase 1, STK38 {ECO:0000312|EMBL:AAH120851} |
| Target/Specificity | STK38 (AAH12085, 365 a.a. ~ 465 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | STK38 Antibody (monoclonal) (M11) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Fujiki R, et al. Nature, 2009 May 21. PMID 19377461.MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes. Chiba S, et al. Curr Biol, 2009 Apr 28. PMID 19327996.NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis. Vichalkovski A, et al. Curr Biol, 2008 Dec 9. PMID 19062280.A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, et al. Biol Psychiatry, 2009 Apr 1. PMID 19058789.Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. Hirabayashi S, et al. Oncogene, 2008 Jul 17. PMID 18362890.
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