癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
STX8 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant STX8.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UNK0 |
| Other Accession | BC009713 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 2H1-1D11 |
| Calculated MW | 26907 Da |
| Gene ID | 9482 |
|---|---|
| Other Names | Syntaxin-8, STX8 |
| Target/Specificity | STX8 (AAH09713, 1 a.a. ~ 236 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | STX8 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Genetic risk profiling and prediction of disease course in Crohn's disease patients. Henckaerts L, et al. Clin Gastroenterol Hepatol, 2009 Sep. PMID 19422935.Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. Weersma RK, et al. Am J Gastroenterol, 2009 Mar. PMID 19174780.Differential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8. He Y, et al. J Lipid Res, 2009 Mar. PMID 18980942.Interaction between syntaxin 8 and HECTd3, a HECT domain ligase. Zhang L, et al. Cell Mol Neurobiol, 2009 Feb. PMID 18821010.
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