癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TAF7 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant TAF7.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q15545 |
| Other Accession | BC032737 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2C5 |
| Calculated MW | 40259 Da |
| Gene ID | 6879 |
|---|---|
| Other Names | Transcription initiation factor TFIID subunit 7, RNA polymerase II TBP-associated factor subunit F, Transcription initiation factor TFIID 55 kDa subunit, TAF(II)55, TAFII-55, TAFII55, TAF7, TAF2F, TAFII55 |
| Target/Specificity | TAF7 (AAH32737, 130 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TAF7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II.
REFERENCES
1.Core promoter factor TAF9B regulates neuronal gene expression.Herrera FJ, Yamaguchi T, Roelink H, Tjian RElife (Cambridge). 2014 Jul 8;3:e02559. doi: 10.7554/eLife.02559.2.Taf7l cooperates with Trf2 to regulate spermiogenesis.Zhou H, Grubisic I, Zheng K, He Y, Wang PJ, Kaplan T, Tjian RProc Natl Acad Sci U S A. 2013 Oct 15;110(42):16886-91. doi: 10.1073/pnas.1317034110. Epub 2013 Sep 30.3.Dual functions of TAF7L in adipocyte differentiation.Zhou H, Kaplan T, Li Y, Grubisic I, Zhang Z, Wang PJ, Eisen MB, Tjian R.elife. 2013;2:e00170. doi: 10.7554/eLife.00170. Epub 2013 Jan 8.4.Core promoter recognition complex changes accompany liver development.D'Alessio JA, Ng R, Willenbring H, Tjian R.Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3906-11. Epub 2011 Feb 22.
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