癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TK1 Antibody (monoclonal) (M05)
Mouse monoclonal antibody raised against a full length recombinant TK1.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P04183 |
| Other Accession | BC007986 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3F9 |
| Calculated MW | 25469 Da |
| Gene ID | 7083 |
|---|---|
| Other Names | Thymidine kinase, cytosolic, TK1 |
| Target/Specificity | TK1 (AAH07986.1, 1 a.a. ~ 234 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TK1 Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Clinical relevance of thymidine kinase for the diagnosis, therapy monitoring and prognosis of non-operable lung cancer. Holdenrieder S, et al. Anticancer Res, 2010 May. PMID 20592392.Regulation and functional contribution of thymidine kinase 1 in repair of DNA damage. Chen YL, et al. J Biol Chem, 2010 Aug 27. PMID 20554529.Thymidine kinase 1 is a potential marker for prognosis and monitoring the response to treatment of patients with breast, lung, and esophageal cancer and non-Hodgkin's lymphoma. He E, et al. Nucleosides Nucleotides Nucleic Acids, 2010 Jun. PMID 20544519.Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage. Skovgaard T, et al. Nucleosides Nucleotides Nucleic Acids, 2010 Jun. PMID 20544518.
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