癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TRPC4AP Antibody (monoclonal) (M07)
Mouse monoclonal antibody raised against a partial recombinant TRPC4AP.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | Q8TEL6 |
| Other Accession | NM_015638 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3G4 |
| Calculated MW | 90852 Da |
| Gene ID | 26133 |
|---|---|
| Other Names | Short transient receptor potential channel 4-associated protein, Trp4-associated protein, Trpc4-associated protein, Protein TAP1, TNF-receptor ubiquitous scaffolding/signaling protein, Protein TRUSS, TRPC4AP, C20orf188, TRRP4AP |
| Target/Specificity | TRPC4AP (NP_056453, 341 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TRPC4AP Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. Choi SH, et al. Genes Dev, 2010 Jun 15. PMID 20551172.The frequency of the TRPC4AP haplotype in Alzheimer's patients. Poduslo SE, et al. Neurosci Lett, 2009 Feb 6. PMID 19059308.Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis. Poduslo SE, et al. Am J Med Genet B Neuropsychiatr Genet, 2009 Jan 5. PMID 18449908.Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Angers S, et al. Nature, 2006 Oct 5. PMID 16964240.TRUSS, a tumor necrosis factor receptor-1-interacting protein, activates c-Jun NH(2)-terminal kinase and transcription factor AP-1. Soond SM, et al. FEBS Lett, 2006 Aug 21. PMID 16876162.
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