癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TTC3 Antibody (monoclonal) (M09)
Mouse monoclonal antibody raised against a partial recombinant TTC3.
- 产品详情
- 实验流程
Application 
| E |
|---|---|
| Primary Accession | P53804 |
| Other Accession | NM_003316 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2D10 |
| Calculated MW | 229869 Da |
| Gene ID | 7267 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase TTC3, 632-, Protein DCRR1, RING finger protein 105, TPR repeat protein D, Tetratricopeptide repeat protein 3, TPR repeat protein 3, TTC3, DCRR1, RNF105, TPRD |
| Target/Specificity | TTC3 (NP_003307, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | TTC3 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt. Suizu F, et al. Dev Cell, 2009 Dec. PMID 20059950.The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase. Berto G, et al. J Cell Sci, 2007 Jun 1. PMID 17488780.Functional proteomics mapping of a human signaling pathway. Colland F, et al. Genome Res, 2004 Jul. PMID 15231748.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
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