癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
UBE2Q2 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a partial recombinant UBE2Q2.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q8WVN8 |
| Other Accession | NM_173469 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2H3 |
| Calculated MW | 42818 Da |
| Gene ID | 92912 |
|---|---|
| Other Names | Ubiquitin-conjugating enzyme E2 Q2, Ubiquitin carrier protein Q2, Ubiquitin-protein ligase Q2, UBE2Q2 |
| Target/Specificity | UBE2Q2 (NP_775740, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | UBE2Q2 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
New loci associated with kidney function and chronic kidney disease. K?ttgen A, et al. Nat Genet, 2010 May. PMID 20383146.Overexpression of the novel human gene, UBE2Q2, in breast cancer. Nikseresht M, et al. Cancer Genet Cytogenet, 2010 Mar. PMID 20193842.Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer. Maeda H, et al. Mol Cancer Res, 2009 Sep. PMID 19723876.Inactivation of the ubiquitin conjugating enzyme UBE2Q2 causes a prophase arrest and enhanced apoptosis in response to microtubule inhibiting agents. Banerjee S, et al. Oncogene, 2007 Oct 4. PMID 17471241.Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours. Seghatoleslam A, et al. Biochem Biophys Res Commun, 2006 Jan 6. PMID 16300736.
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