癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
UGT2B10 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant UGT2B10.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P36537 |
| Other Accession | NM_001075 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 2D9 |
| Calculated MW | 60774 Da |
| Gene ID | 7365 |
|---|---|
| Other Names | UDP-glucuronosyltransferase 2B10, UDPGT 2B10, UGT2B10 |
| Target/Specificity | UGT2B10 (NP_001066, 62 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | UGT2B10 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption. Berg JZ, et al. Cancer Epidemiol Biomarkers Prev, 2010 Jun. PMID 20501767.Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. Chen G, et al. Pharmacogenet Genomics, 2008 Mar. PMID 18300939.Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism. Chen G, et al. Cancer Res, 2007 Oct 1. PMID 17909004.Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. Kaivosaari S, et al. Mol Pharmacol, 2007 Sep. PMID 17576790.Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Liu T, et al. J Proteome Res, 2005 Nov-Dec. PMID 16335952.
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