癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
USP33 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant USP33.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF, IP, E |
|---|---|
| Primary Accession | Q8TEY7 |
| Other Accession | NM_015017 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 5B5 |
| Calculated MW | 106727 Da |
| Gene ID | 23032 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 33, Deubiquitinating enzyme 33, Ubiquitin thioesterase 33, Ubiquitin-specific-processing protease 33, VHL-interacting deubiquitinating enzyme 1, hVDU1, USP33, KIAA1097, VDU1 |
| Target/Specificity | USP33 (NP_055832, 327 a.a. ~ 426 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | USP33 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility. Meulenbelt I, et al. Ann Rheum Dis, 2010 Aug 19. PMID 20724312.Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration. Yuasa-Kawada J, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19706539.Midline crossing and Slit responsiveness of commissural axons require USP33. Yuasa-Kawada J, et al. Nat Neurosci, 2009 Sep. PMID 19684588.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization. Berthouze M, et al. EMBO J, 2009 Jun 17. PMID 19424180.
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