癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
USP9Y Antibody (monoclonal) (M05)
Mouse monoclonal antibody raised against a partial recombinant USP9Y.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | O00507 |
| Other Accession | NM_004654 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2D3 |
| Calculated MW | 291077 Da |
| Gene ID | 8287 |
|---|---|
| Other Names | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y, Deubiquitinating enzyme FAF-Y, Fat facets protein-related, Y-linked, Ubiquitin thioesterase FAF-Y, Ubiquitin-specific protease 9, Y chromosome, Ubiquitin-specific-processing protease FAF-Y, USP9Y, DFFRY |
| Target/Specificity | USP9Y (NP_004645, 3 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | USP9Y Antibody (monoclonal) (M05) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins.
REFERENCES
Spermatogenesis in a man with complete deletion of USP9Y. Luddi A, et al. N Engl J Med, 2009 Feb 26. PMID 19246359.Partial AZFc deletions and duplications: clinical correlates in the Italian population. Giachini C, et al. Hum Genet, 2008 Nov. PMID 18807255.Tracking microdeletions of the AZF region in a patrilineal line of infertile men. Rodovalho RG, et al. Genet Mol Res, 2008 Jul 8. PMID 18752188.Y chromosome haplogroups may confer susceptibility to partial AZFc deletions and deletion effect on spermatogenesis impairment. Yang Y, et al. Hum Reprod, 2008 Sep. PMID 18579508.Genetic variants of Y chromosome are associated with a protective lipid profile in black men. Russo P, et al. Arterioscler Thromb Vasc Biol, 2008 Aug. PMID 18511697.
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