CTSD Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| IF, IHC-P, WB |
---|---|
Primary Accession | P07339 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Calculated MW | 44552 Da |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 1509 |
---|---|
Other Names | Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD |
Dilution | IF~~1:25 IHC-P~~1:100~500 WB~~1:1000 |
Target/Specificity | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CTSD Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTSD |
---|---|
Synonyms | CPSD |
Function | Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
Cellular Location | Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380) |
Tissue Location | Expressed in the aorta extracellular space (at protein level) (PubMed:20551380). Expressed in liver (at protein level) (PubMed:1426530). |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.

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