癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SSPN Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB |
|---|---|
| Primary Accession | Q14714 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 26618 Da |
| Isotype | Rabbit IgG |
| Antigen Source | Human |
| Gene ID | 8082 |
|---|---|
| Antigen Region | 6-34 aa |
| Other Names | SSPN;KRAG; Sarcospan; Sarcospan; K-ras oncogene-associated protein; Sarcospan; Kirsten-ras-associated protein |
| Dilution | WB~~1:1000 |
| Target/Specificity | This SSPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human SSPN. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SSPN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SSPN |
|---|---|
| Synonyms | KRAG |
| Function | Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma Postsynaptic cell membrane; Multi-pass membrane protein. Note=Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. |
| Tissue Location | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.
REFERENCES
Crosbie R.H., et al. J. Biol. Chem. 272:31221-31224(1997).
Crosbie R.H., et al. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Wiemann S., et al. Genome Res. 11:422-435(2001).
Heighway J., et al. Genomics 35:207-214(1996).
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