癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DANRE pou3f3a Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P56224 |
| Reactivity | Human, Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47216 Da |
| Antigen Region | 381-407 aa |
| Gene ID | 30386 |
|---|---|
| Other Names | POU domain, class 3, transcription factor 3-A, Brain-specific homeobox/POU domain protein 11, Brain-11, zfBrn-11, Class III POU domain protein taichi, POU domain protein 12, ZP-12, pou3f3a, brn-11, brn11, pou12, tai-ji, zp12, zp12pou |
| Target/Specificity | This DANRE pou3f3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-407 amino acids from the C-terminal region of DANRE pou3f3a. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DANRE pou3f3a Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | pou3f3a |
|---|---|
| Synonyms | brn-1.1, brn1.1, pou12, tai-ji, zp12, zp |
| Function | Transcription factor that may play important roles in patterning the embryonic brain. |
| Cellular Location | Nucleus. |
| Tissue Location | Predominantly expressed in the embryonic and adult central nervous system. In adults, isoform 2 is expressed in the brain, ovary, basal cells of the skin and muscle satellite cells |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Transcription factor that may play important roles in patterning the embryonic brain.
REFERENCES
Spaniol P., et al. Nucleic Acids Res. 24:4874-4881(1996).
Lim J.H., et al. Biochim. Biophys. Acta 1397:253-256(1998).
Huang S., et al. Mech. Dev. 71:23-35(1998).
Shah D., et al. Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Sampath K., et al. Biochem. Biophys. Res. Commun. 219:565-571(1996).
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