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>   首页   >   产品   >   蛋白产品   >   细胞因子   >   生长因子   >   hGM-CSF   

hGM-CSF

     
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Product Information
Species Human
Sequence MAPARSPSPS TQPWEHVNAI QEALRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Purity > 95 % as analyzed by SDS-PAGE.
Endotoxin Level <1.0EU/ µg, determined by LAL method.
Formulation Lyophilized after extensive dialysis against 10 mM PB, pH7.0.
Reconstitution Reconstituted in ddH2O at 100 µg/ml.
Additional Information
Target Background Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF), a hematopoietic growth factor, is mainly involved in granulopoiesis and monocytopoiesis. It is produced by T-cells and macrophages in response to antigens, and by endothelial cells and fibroblasts following induction of variouscytokines [1]. A monomeric protein of 127 amino acidswith six glycosylation sites and two intra disulfide bonds[2,3], glycosylated and non-glycosylated hGM-CSFs show similar biological activities[4]. Other than its connection to the growth and development of granulocytes and macrophages, it is also indispensable for the proliferation of erythroid and megakaryocytic cells[5].

Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) produced in P. pastoris a glycosylated polypeptide. A fully biologically active molecule, rhGM-CSF has a molecular mass of 26-32kDa analyzed by SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques at .
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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