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MIA-2, Human

     
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Product Information
Species Human
Sequence LESTKLLADL KKCGDLECEA LINRVSAMRD YRGPDCRYLN FTKGEEISVY VKLAGEREDL
WAGSKGKEFG YFPRDAVQIE EVFISEEIQM STKESDFLCL
Purity > 97 % by SDS-PAGE and HPLC analyses.
Endotoxin Level Less than 1 EU/ µg of rHuMIA2 as determined by LAL method.
Formulation Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Additional Information
Target Background MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3)-like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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