癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Protein S100-A4
- 产品详情
- 实验流程
| Primary Accession | NP_002952.1 |
|---|---|
| Species | Human |
| Sequence | MACPLEKALD VMVSTFHKYS GKEGDKFKLN KSELKELLTR ELPSFLGKRT DEAAFQKLMS NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGFPDKQPRK K |
| Purity | > 90% as analyzed by SDS-PAGE. |
| Endotoxin Level | < 1 EU/ µg, determined by LAL method. |
| Formulation | Lyophilized after extensive dialysis against 20 mM Tris-HCl, 100 mM NaCl , pH8.0. |
| Reconstitution | Reconstituted in ddH2O at 200 µg/ml. |
| Target Background | S100 calcium-binding protein A4 (S100A4) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A4 promotes metastasis in several experimental animal models, and S100A4 protein expression is associated with differential patient outcome in a number of tumor types. S100A4 is localized in the nucleus, cytoplasm, and extracellular space and possesses a wide range of biological functions such as regulation of angiogenesis, cell survival, motility, and invasion. Recombinant S100 calcium-binding protein A4 (S100A4) produced in E. coli is a single chain containing 101 amino acids with molecular mass of 11.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at . |
|---|
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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