注册 | 登录
点击这里给我发消息
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   BTC   

BTC

     
  • 产品详情
  • 实验流程
Product Information
Primary Accession Q05928
Species Mouse
Sequence MDGNTTRTPE TNGSLCGAPG ENCTGTTPRQ KVKTHFSRCP KQYKHYCIHG RCRFVVDEQT PSCICEKGYF GARCERVDLF Y
Purity > 95% by SDS-PAGE analysis.
Endotoxin Level < 0.2 EU/ µg, determined by LAL method.
Formulation Lyophilized after extensive dialysis against 50mM Tris, 300mM NaCl, pH9.0.
Reconstitution Reconstituted in ddH2O at 100 µg/mL.
Additional Information
Gene ID 12223
Other Names Probetacellulin, Betacellulin, BTC, Btc, Bcn
Target Background Betacellulin is a pleiotropic cytokine that belongs to the Epidermal Growth Factor (EGF) family. Like other members of the EGF family, Betacellulin possesses a conserved sequence of 35-40 amino acids which contain 3 disulfide bonds formed by 6 cysteines. Betacellulin is unique in the EGF family since it can bind and activate a broad spectrum of ErbB receptors. Functionally, Betacellulin plays a role in the development of the pancreas by activating signaling pathways beneficial for the function, survival and regeneration of pancreatic β-cells. Additionally, Betacellulin has potential angiogenic activities and is important for the growth, development and repair of certain tissues.
Recombinant mouse Betacellulin (rmBetacellulin) produced in E. coli is a single non-glycosylated polypeptide chain containing 81 amino acids. A fully biologically active molecule, rmBetacellulin has a molecular mass of 9.2 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at .
Protein Information
Name Btc
Synonyms Bcn
Function Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Cellular Location [Betacellulin]: Secreted, extracellular space.
Tissue Location Found in several mouse tissues including kidney, uterus and liver, as well as in beta tumor cell line and MCF-7 cells It is not detected in the brain
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价